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J Integr Bioinform 2010,Jan,01;7(1):141; (PMID: 20508300)
[...]In this context, a new tool has been developed at the Spanish Centro Nacional de Biotecnologia Proteomics Facility termed PIKE (Protein information and Knowledge Extractor) that allows researchers to control, filter and access specific information from genomics and proteomic databases, to understand the role and relationships of the proteins identified in the experiments. Additionally, an EU funded project, ProDac, has coordinated systematic data collection in public standards-compliant repositories like PRIDE. This will cover all aspects from generating MS data in the laboratory, assembling the whole annotation information and storing it together with identifications in a standardised format.[...]
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Clin Ther 2009,Dec,01;31(12):2860-72; (PMID: 20110025)
[...]However, its efficacy and tolerability versus NSAIDs have not been reported in an Asian population. OBJECTIVE: This study compared the efficacy and tolerability of SAMe 1200 mg/d and nabumetone 1000 mg/d in Korean patients with knee OA. METHODS: This study was an 8-week, multicenter, randomized, double-blind, double-dummy, Phase IV clinical trial.[...]
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Pharmacol Res 2009,Oct,01;60(4):254-63; (PMID: 19467328)
[...]RESULTS: Seventy-five comparative trials were ultimately included for analyses. Regarding global efficacy, piroxicam was more effective than naproxen [OR=1.37 (1.05; 1.77)] and nabumetone [OR=1.72 (1.26; 2.34)], while equivalent to other NSAIDS [OR=1.06 (0.96; 1.18)]. For pain and articular [...]
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Drug Metab Dispos 2009,May,01;37(5):1017-24; (PMID: 19204080)
Nabumetone, a widely used nonsteroidal anti-inflammatory drug, requires biotransformation into 6-methoxy-2-naphthylacetic acid (6-MNA), a close structural analog to [...]
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JNMA J Nepal Med Assoc 2009,Apr,01;48(174):121-5; (PMID: 20387351)
[...], a NSAID is widely used in the treatment of pain and inflammation associated with osteoarthritis. Nabumetone, a recently developed preferential cyclo-oxygenase 2 inhibitor has also proved to be equally effective.[...]
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Talanta 2009,Jan,15;77(3):925-42; (PMID: 19064072)
[...]The present review submitted the use of various analytical techniques for the determination of oxicams, nimesulide and nabumetone. This review covers the time period from 1990 to 2008 during which over 200 analytical methods including all types of chromatographic, spectrophotometric and voltammetric techniques were reported.[...]
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Basic Clin Pharmacol Toxicol 2009,Jan,01;104(1):17-21; (PMID: 19152549)
[...]inhibition in drug safety. We compared the effects of acetylsalicylic acid, ibuprofen, nabumetone and nimesulide on COX-1 and COX-2 pathways in healthy volunteers in an ex vivo set-up using single oral doses commonly used to treat [...]
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Proteomics 2009,Jan,01;9(2):218-22; (PMID: 19105180)
ProDaC (Proteomics Data Collection), a "Coordination Action" within the 6(th) EU framework programme, was created to support the collection, distribution and public availability of data from proteomics experiments.[...]
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Nucl Med Biol 2009,Jan,01;36(1):99-106; (PMID: 19181274)
[...] and monkey sera were performed with site-selective displacers of specific binding sites: 400 microM 6-methoxy-2-naphthylacetic acid (6MNA; a major nabumeton metabolite) as a serum albumin Site II inhibitor and 400 microM erythromycin (ETC) as an alpha(1)-acid glycoprotein (AGP) site inhibitor.[...]
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Cochrane Database Syst Rev 2009,Jan,01;(4):CD007548; (PMID: 19821428)
BACKGROUND: Nabumetone is a non-steroidal anti-inflammatory drug (NSAID) used mainly in treating pain associated with arthritis.[...]
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