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Postgrad Med 2010,Jul,01;122(4):158-69; (PMID: 20675978)
OBJECTIVE: To assess the efficacy and tolerability of once-daily cyclobenzaprine extended release (CER) 15 and 30 mg in relieving acute muscle spasm. METHODS: This is a pooled analysis of 2 randomized, double-blind, [...]
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Neuroscience 2010,Jun,30;168(2):551-63; (PMID: 20381591) [FULL TEXT AVAILABLE]
[...] in HEK293 cells over-expressing human TLR4. Six exhibited mild (desipramine), moderate (mianserin, cyclobenzaprine, imiprimine, ketotifen) or strong (amitriptyline) TLR4 inhibition, and no TLR4[...]
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J Anal Toxicol 2010,Jan,01;34(2):64-72; (PMID: 20223097)
[...]An analytical procedure for the determination of widely prescribed drugs for the treatment of depression and anxiety disorders, including amitriptyline, cyclobenzaprine, imipramine, dothiepin, doxepin, fluoxetine, sertraline, trimipramine, protriptyline, [...]
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CJEM 2010,Jan,01;12(1):39-44; (PMID: 20078917)
[...]METHODS: We performed a double-blinded, randomized controlled trial of adults with cervical strains from motor vehicle collisions or from falls who presented to a suburban academic emergency department (ED). Patients were randomly assigned to receive ibuprofen 800 mg, cyclobenzaprine 5 mg or both, 3 times daily as needed for up to 7 days. Outcome measures included a [...]
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Am J Emerg Med 2009,May,01;27(4):509-10; author reply 510; (PMID: 19555629)
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Curr Med Res Opin 2009,May,01;25(5):1179-96; (PMID: 19323613)
OBJECTIVE: To evaluate efficacy and tolerability of once-daily cyclobenzaprine extended release (CER) 15- and 30-mg capsules in patients with muscle spasm associated with acute, [...]
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Gen Hosp Psychiatry 2009,May,01;31(3):206-19; (PMID: 19410099)
[...]) or tramadol; (3) gabapentin, duloxetine or pregabalin if neuropathic pain; (4) cyclobenzaprine, pregabalin, duloxetine, or milnacipran for fibromyalgia; (5) topical analgesics (capsaicin, [...]
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Int J Clin Pharmacol Ther 2009,Apr,01;47(4):269-74; (PMID: 19356393)
OBJECTIVE: To evaluate the systemic bioavailability of a new controlled release cyclobenzaprine tablet, and the influence of a high fat meal on its bioavailability. SUBJECTS, MATERIALS AND METHODS: 24 and 12 healthy male subjects were recruited for the bioavailability and influence of diet studies, respectively.[...]
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Am J Health Syst Pharm 2009,Jan,15;66(2):142-8; (PMID: 19139478)
[...]) 15 mg by mouth once five days prior for a school examination, and hydrocodone-acetaminophen and cyclobenzaprine for pain. His social history revealed a recent increase in his exercise regimen, and his last alcoholic beverage was consumed five days prior.[...]
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Drugs Aging 2009,Jan,01;26(2):95-101; (PMID: 19220066)
BACKGROUND AND OBJECTIVE: The clinical utility of cyclobenzaprine for the treatment of muscle spasm associated with acute, painful musculoskeletal conditions is limited by cholinergic adverse effects associated with its use.[...]
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