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Results for "SELP": Pubmed ( 5,677 ) | Free Full Text ( 427 ) | U.S. Grants ( 328 )

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Role of selenoprotein P in Alzheimer's disease.

Ethn Dis 2010,Dec,21;20(1 Suppl 1):S1-92-5; (PMID: 20521393) [FULL TEXT AVAILABLE]
INTRODUCTION: Selenoprotein P (SelP) plays a critical role in neuronal survival and is associated with Alzheimer's pathology. We sought to determine a potential neuroprotective role for [...]

Soluble P selectin in synovial fluid level is correlated with the radiographic severity of knee osteoarthritis.

Clin Chim Acta 2010,Oct,09;411(19-20):1529-31; (PMID: 20580699)
[...] is a feature of the disease process in Osteoarthritis (OA). The clinical significance of P selectin (Ps) in OA has not been adequately studied and the association between Ps[...]

Endothelialization of PVA/gelatin cryogels for vascular tissue engineering: Effect of disturbed shear stress conditions.

J Biomed Mater Res A 2010,Sep,15;94(4):1080-90; (PMID: 20694975)
[...] cells on the cryogel surface, whereas abrupt application caused widespread removal. Under static conditions, Selectin-P expression decreased, whereas both inter-cellular adhesion molecule (ICAM) and platelet endothelial cell adhesion molecule (PECAM)-I expression increased on cryogels over a 10-day culture period.[...]

Characterization of distinct mesenchymal-like cell populations from human skeletal muscle in situ and in vitro.

Exp Cell Res 2010,Sep,10;316(15):2513-26; (PMID: 20430024)
[...]Immunohistology revealed labeling of cells by markers of mesenchymal (CD13, CD29, CD44, CD47, CD49, CD62, CD73, CD90, CD105, CD146, and CD15 in this study), myogenic (CD56), [...]

Structural comparison and classification of alpha-helical transmembrane domains based on helix interaction patterns.

Proteins 2010,Sep,01;78(12):2587-99; (PMID: 20552684)
[...]Here, a new and completely membrane protein specific structural classification system is introduced that classifies alpha-helical membrane proteins according to common helix architectures. Each membrane protein is represented by a helix interaction graph depicting transmembrane helices with their pairwise [...]

Human L-selectin preferentially binds synthetic glycosulfopeptides modeled after endoglycan and containing tyrosine sulfate residues and sialyl Lewis x in core 2 O-glycans.

Glycobiology 2010,Sep,01;20(9):1170-85; (PMID: 20507883)
[...]Interestingly, under similar conditions, neither L-selectin nor T lymphocytes showed appreciable binding to the sulfated carbohydrate epitope 6-sulfo-SLe(x). P-selectin also bound to endoglycan-based GSPs but with lower affinity than toward GSPs modeled after PSGL-1[...]

Targeting P-selectin in acute pancreatitis.

Expert Opin Ther Targets 2010,Sep,01;14(9):899-910; (PMID: 20608786)
[...]pathways promoting a severe life-threatening course of AP are the subject of ongoing investigations. P-selectin has been shown to play a central role in the complex pathophysiology in AP as well as various other inflammatory conditions.[...]

The role of thromboprophylaxis in cancer patients: emerging data.

Curr Opin Hematol 2010,Sep,01;17(5):450-6; (PMID: 20601873)
[...]malignancy, including leukocyte and platelet counts, tissue factor, prothrombin split products, D-dimer, P-selectin, factor VIII and C-reactive protein. Recent and ongoing clinical trials have focused on VTE[...]

Impaired innate immune response and enhanced pathology during Citrobacter rodentium infection in mice lacking functional P-selectin.

Cell Microbiol 2010,Sep,01;12(9):1250-71; (PMID: 20345490)
[...]), P-, E- and L-selectin were infected using a Citrobacter-induced colitis model. Infected mice lacking PSGL-1 or P-selectin showed a more pronounced morbidity associated with higher bacterial load, elevated IL-12 p70, TNF-alpha, [...]

Pneumoproteins and inflammatory biomarkers in asphalt pavers.

Biomarkers 2010,Sep,01;15(6):498-507; (PMID: 20528258)
[...] concentration than smokers not reporting wheezing (5.7 vs 8.6 microg l(-1); p = 0.05). Cholesterol, P-selectin and ICAM-1 were lower in pavers and operators at the end compared with the start of the season.[...]
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