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Biomaterials 2010,Jan,01;31(2):366-74; (PMID: 19822361)
[...]MNPs-DMSA at concentrations as high as 1 x 10(15) nanoparticles/mL had no toxic effects on macrophages, as evidenced by 3-(4, 5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide (MTT) assay. Notably, MNPs-DMSA up-regulated the mRNA expression of E-, L- and P-selectin and macrophage-1 antigen in the murine lung. Upregulation of these cell adhesion molecules was associated with an increased concentration of [...]
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J Control Release 2009,Dec,03;140(2):100-7; (PMID: 19666063)
To improve ultrasound contrast agents targeted to the adhesion molecules P-selectin and VCAM-1 for the purpose of molecular imaging of atherosclerotic plaques, perfluorocarbon-filled phospholipid microbubble contrast agents were coupled by a polyethylene glycol-biotin-streptavidin bridge with mAb MVCAM.A(429), a sialyl Lewis(x) polymer (PAA-sLe(x)), or both (dual).[...]
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Eur J Nutr 2009,Dec,01;48(8):475-81; (PMID: 19633966)
[...] platelets from fasted subjects at various concentrations and different time points. Platelet activation, determined as expression of surface markers CD62 and CD63, and the presence of the receptor for AGEs (RAGE) in platelet membranes was measured by flow cytometric analysis using specific antibodies.[...]
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Pulm Pharmacol Ther 2009,Dec,01;22(6):593-602; (PMID: 19744573)
[...] of some genes (Tnf, Cxcl2) and downregulation of others (Cxcl10, Timp1, Selp, Il6). At the protein level, TSA reduced the stimulated release of TNF, MIP-2alpha and IL-6[...]
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Chem Biol Drug Des 2009,Dec,01;74(6):596-610; (PMID: 19843078)
P-selectin is a promising target for developing novel atherosclerosis drugs. To understand the structure-activity correlation of quinolines-based [...]
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Clin Immunol 2009,Nov,01;133(2):257-64; (PMID: 19665434)
[...]These cells uniformly bind to the vascular adhesion molecule E-selectin, yet only a subset binds to P-selectin. The latter cells are distinguished by the mAb CHO-131, and are enriched in psoriasis[...]
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Nephrol Dial Transplant 2009,Nov,01;24(11):3461-8; (PMID: 19561150)
[...]During haemodialysis (HD), both an increase in the expression of the platelet (PLT) cell surface molecule P-selectin (CD62p) and the release of intra-granular substances, such as platelet factor 4 (PF4) and ss-thromboglobulin (BTG), have been described.[...]
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Blood Cells Mol Dis 2009,Nov,01;43(3):230-4; (PMID: 19654073)
[...]Twenty apparently healthy individuals matched for age and sex, formed the control group. Measurements of sVCAM-1, sICAM-1, sTM, P-selectin, E-selectin and CRP levels were performed using immunoassays. We found that all endothelial[...]
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Thromb Res 2009,Nov,01;124(5):572-7; (PMID: 19631364)
[...] as measured by VASP-assay and VerifyNowP2Y(12) (r = -0.29, p<0.05), and between VASP-assay and the expression of P-selectin (r = 0.29, p<0.05) as measured by flow cytometry when platelets were stimulated with 5 microM [...]
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Am J Clin Nutr 2009,Nov,01;90(5):1144-50; (PMID: 19776136)
[...] was significantly lower (P = 0.005, 0.028, and 0.001, respectively) after C+M intake than after M intake. In addition, serum concentrations of the soluble endothelium-derived adhesion molecules P-selectin and intercellular adhesion molecule-1 were significantly lower (both P = 0.007) after C+M intake than after M intake.[...]
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