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Results for "Rohypnol": Pubmed ( 1,756 ) | Free Full Text ( 38 ) | U.S. Grants ( 28 )

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Overexpression of translocator protein in inflammatory bowel disease: Potential diagnostic and treatment value.

Inflamm Bowel Dis 2010,Sep,01;16(9):1476-87; (PMID: 20222126)
[...] drug ligands PK 11195 or Ro5-4864 increased both the rate of colon ulceration and regeneration, whereas administration of the TSPO drug ligand flunitrazepam partially prevented this pathology. These data correlated with changes in proinflammatory cytokine plasma levels, as well as [...]

Development and validation of an EI-GC-MS method for the determination of benzodiazepine drugs and their metabolites in blood: Applications in clinical and forensic toxicology.

J Pharm Biomed Anal 2010,Aug,01;52(4):609-14; (PMID: 20172681)
[...]medazepam, flurazepam, fludiazepam, tetrazepam, chlordiazepoxide, clobazam, midazolam, flunitrazepam, 7-amino-flunitrazepam, triazolam, prazepam, nimetazepam, nitrazepam, temazepam, lormetazepam, [...]

Effect of hypnotic drugs on body balance and standing steadiness.

Sleep Med Rev 2010,Aug,01;14(4):259-67; (PMID: 20171127)
[...]Drugs that were searched were nitrazepam, triazolam, lorazepam, temazepam, loprazolam, flunitrazepam, flurazepam, and the Z-drugs zopiclone, zolpidem and zaleplon. RESULTS: A total of 57 studies were eligible for inclusion.[...]

Assessment of abuse potential of benzodiazepines from a prescription database using 'doctor shopping' as an indicator.

CNS Drugs 2010,Jul,01;24(7):611-20; (PMID: 20527997)
[...]clorazepate (5 mg, 10 mg, 50 mg), diazepam (1 mg, 5 mg, 10 mg), flunitrazepam 1 mg, lorazepam (1 mg, 2.5 mg) and tetrazepam 50 mg. For each patient, the quantities prescribed, dispensed and obtained by doctor shopping (i.e. overlap between prescriptions from different prescribers) were computed.[...]

Immunomodulating properties of gamma-hydroxybutyrate (GHB), flunitrazepam and ethanol in 'club drugs' users.

Addict Biol 2010,Jul,01;15(3):336-45; (PMID: 20456291)
[...]Drug conditions were: a single oral dose of GHB (40 mg/kg or 60 mg/kg), ethanol (0.7 g/kg), flunitrazepam (1.25 mg) and placebo. Acute GHB produced a time-dependent immune impairment in the first 4 hours after drug administration associated with an increase in [...]

A prospective naturalistic multicentre study of intravenous medications in behavioural emergencies: haloperidol versus flunitrazepam.

Psychiatry Res 2010,Jun,30;178(1):182-5; (PMID: 20452043)
[...]FNP group) (68% [S.D. 17] vs. 54% [S.D. 31], P=0.02). The mean dose of flunitrazepam in the HAL+FNP group was significantly lower than that in the FNP+HAL-group (1.3 mg vs. 3.5 mg, P=0.0003).[...]

Flunitrazepam in combination with alcohol engenders high levels of aggression in mice and rats.

Pharmacol Biochem Behav 2010,May,01;95(3):292-7; (PMID: 20156476)
[...]. OBJECTIVES: To assess firstly the effects of ethanol, secondly the effects of flunitrazepam, a so-called club drug, and thirdly the effects of flunitrazepam plus alcohol on aggression in [...]

[Analysis of addictive behaviours among new prisoners in France using the OPPIDUM program]

Encephale 2010,Apr,01;36(2):122-31; (PMID: 20434629)
[...]In comparison to other subjects, the prisoners consume more products, more illicit ones and more benzodiazepines like flunitrazepam and clonazepam before their imprisonment. The medicines are consumed with higher doses and are more often obtained illegally (35% vs 14%).[...]

New 1,5-benzodiazepine compounds: activity at native GABA(A) receptors.

Neuroscience 2010,Mar,31;166(3):917-23; (PMID: 20096335)
[...]cerebellar granules in culture. Their effects were compared to those of a 1,4-benzodiazepine agonist, flunitrazepam and the already known 1,5-benzodiazepine antiepileptic clobazam. The effects were evaluated for the two different GABA(A) receptor populations present in these neurons, one mediating phasic [...]

A tendency for re-offending in drug-facilitated crime.

Forensic Sci Int 2010,Mar,20;196(1-3):14-7; (PMID: 20116946)
[...]Case #3: The offender stole thousands of Euros using credit cards obtained from 22 different wealthy victims. He employed a cocktail of up to 6 drugs made up of: flunitrazepam, clonazepam, doxylamine, cyamemazine, zolpidem and lorazepam. Drugs were detected in all victims' [...]
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