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Results for "Cromolyn": Pubmed ( 5,173 ) | Free Full Text ( 110 ) | U.S. Grants ( 10 )

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Effects of mast cell modulation on early host response to implanted synthetic meshes.

Hernia 2010,Oct,01;14(5):511-6; (PMID: 20526725)
[...] with poliglecaprone (Ultrapro), and 3-dimensional macroporous polyester (Parietex) meshes were implanted subcutaneously in C57BL/6 J mice with and without cromolyn (MC stabilizer/suppressant) treatment (50 mg/kg, daily IP). Two weeks post-implantation, all meshes were explanted and evaluated histologically using H&E and trichrome stains.[...]

Treatment of allergic conjunctivitis: results of a 1-month, single-masked randomized study.

Eur J Ophthalmol 2010,Sep,01;20(5):811-8; (PMID: 20383847)
[...]allergic conjunctivitis were randomized to receive 1 of the following 8 treatments twice daily: cromolyn sodium/chlorpheniramine maleate, diclofenac, epinastine, fluorometholone, ketotifen, levocabastine, naphazoline[...]

Mast cell degranulation mediates bronchoconstriction via serotonin and not via renin release.

Eur J Pharmacol 2010,Aug,25;640(1-3):185-9; (PMID: 20462506)
[...] (10 micromol/l), the angiotensin II type 1 (AT1) receptor blocker irbesartan (1 micromol/l), the mast cell stabilizer cromolyn (0.3 mmol/l), the 5-HT2A/2C receptor antagonist ketanserin (0.1 micromol/l) or the alpha1-adrenoceptor antagonist phentolamine (1 micromol/l).[...]

Noncovalent polymerization and assembly in water promoted by thermodynamic incompatibility.

J Phys Chem B 2010,Aug,19;114(32):10357-67; (PMID: 20701370)
[...]poly(vinyl pyrrolidone) (PVP) also promotes liquid crystal (LC) droplet formation by disodium cromoglycate (5'DSCG) solvated in water. In the presence of these polymers, the concentration of 5'DSCG needed for forming LC droplets is substantially lower than that needed for forming an LC phase by 5'DSCG alone.[...]

Dry powder aerosols generated by standardized entrainment tubes from alternative sugar blends: 3. Trehalose dihydrate and D-mannitol carriers.

J Pharm Sci 2010,Aug,01;99(8):3430-41; (PMID: 20229601)
[...] therapeutic classes and with a different pharmacological action were employed. Specifically, the four pulmonary drugs were albuterol sulfate, ipratropium bromide monohydrate, disodium cromoglycate, and fluticasone propionate. The two carrier sugars, each representing a different sugar class, were [...]

Dry powder aerosols generated by standardized entrainment tubes from drug blends with lactose monohydrate: 1. Albuterol sulfate and disodium cromoglycate.

J Pharm Sci 2010,Aug,01;99(8):3398-414; (PMID: 20198688)
[...]In contrast, the highest shear SET (tau(s) = 13.143 N/m(2)) gave a lower ED (ED approximately 75-89%) and higher FPF (FPF(6.4) approximately 15-46%). The performance of disodium cromoglycate was superior to albuterol sulfate at given tau(s), as was milled with respect to sieved [...]

Bone mineral density in children treated with daily or periodical inhaled budesonide: the Helsinki Early Intervention Childhood Asthma study.

Pediatr Res 2010,Aug,01;68(2):169-73; (PMID: 20485203)
[...]children used BUD as needed for 1 y; an additional 42 children received disodium cromoglycate (DSCG). Asthma exacerbations were treated with BUD for 2 wk in a dose of 400 microg twice daily in all groups.[...]

Indirect challenge tests: Airway hyperresponsiveness in asthma: its measurement and clinical significance.

Chest 2010,Aug,01;138(2 Suppl):25S-30S; (PMID: 20668015)
[...]exercise-induced bronchoconstriction (EIB). The inhibition of EIB in young children by sodium cromoglycate led to the concept that mast cells were important very early in the onset of [...]

Effects of a german asthma disease management program using sickness fund claims data.

J Asthma 2010,Aug,01;47(6):674-9; (PMID: 20632918)
[...]Hospitalization or oral corticosteroid user rates were comparable in both groups, whereas there are significantly more subjects in the DM group with a prescription of an inhaled corticosteroid and fewer with a prescription of a cromolyn/reproterol combination. There are also less "doctor hoppers" in the DM group, defined as subjects with antiasthmatic drug prescriptions of at least three physicians.[...]

Pancreatic and pulmonary mast cells activation during experimental acute pancreatitis.

World J Gastroenterol 2010,Jul,21;16(27):3411-7; (PMID: 20632444) [FULL TEXT AVAILABLE]
[...] was induced by intraductal infusion of 5% sodium taurodeoxycholate in rats. The mast cell inhibitor cromolyn was administered intraperitoneally (i.p.) 30 min before pancreatitis induction. The pancreatic and pulmonary tissue damage was evaluated histologically and mast cells and their state of activation were evaluated.[...]
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