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Results for "Cromolyn": Medline ( 5,122 ) | Full Text ( 72 ) | Grants ( 9 )

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Effect of oral sodium cromoglycate in 2 children with food-dependent exercise-induced anaphylaxis (FDEIA).

Clin Pediatr (Phila) 2009,Nov,01;48(9):945-50; (PMID: 19483137)
[...]Food-dependent exercise-induced anaphylaxis (FDEIA) was prevented from recurring in 2 children by sodium cromoglycate (SCG) before intake of the causative food. CASE 1: A 14-year-old girl who had suffered recurrent symptoms of [...]

Exploring the ameliorative potential of Punica granatum in dextran sulfate sodium induced ulcerative colitis in mice.

Phytother Res 2009,Nov,01;23(11):1565-74; (PMID: 19367659)
[...] extract and its ellagic acid rich fraction were comparable to sulphasalazine (100 mg/kg, p.o.) and sodium cromoglycate (40 mg/kg i.p). It is concluded that Punica granatum has a potential for ameliorating DSS[...]

Role of mast cells and protease-activated receptor-2 in cyclooxygenase-2 expression in urothelial cells.

Am J Physiol Regul Integr Comp Physiol 2009,Oct,01;297(4):R1127-35; (PMID: 19675284)
[...] protein abundance was prevented by treatment of mice with the mast cell stabilizer sodium cromolyn (10 mg/kg ip) for 4 consecutive days before CYP treatment. Incubation of freshly isolated mouse[...]

Changes in collection efficiency in nylon net filter media through magnetic alignment of elongated aerosol particles.

J Occup Environ Hyg 2009,Oct,01;6(10):648-57; (PMID: 19693722)
[...] aerosols tend to align parallel to surrounding fluid streamlines in shear flows, making their filtration more difficult. However, previous research indicates that composite particles made from cromoglycic acid fibers coated with small nanoscaled magnetite particles can align with an applied magnetic field. The present research explored the effect of magnetically aligning these [...]

A crucial role for TNF-alpha in mediating neutrophil influx induced by endogenously generated or exogenous chemokines, KC/CXCL1 and LIX/CXCL5.

Br J Pharmacol 2009,Oct,01;158(3):779-89; (PMID: 19702783)
[...] treatment. Macrophages and mast cells expressed CXCR2 receptors. Increased macrophage numbers enhanced, while cromolyn sodium (mast cell stabilizer) diminished, LIX/CXCL5-induced neutrophil recruitment. Macrophages and mast cells from immunized mice[...]

RBL-2H3 cells are an imprecise model for mast cell mediator release.

Inflamm Res 2009,Sep,01;58(9):611-8; (PMID: 19301096)
[...]RESULTS: Mediator release was dependent on media composition and degranulation was stimulated by IgE and A23187. Degranulation was inhibited by quercetin, but not by cromoglycate or ketotifen. Transcripts encoding TLR3-5 and 6 were detected in RBL-2H3 cells whereas TLR1-6 and TLR8 were clearly seen in RPMC.[...]

Mast cells are early responders after hypoxia-ischemia in immature rat brain.

Stroke 2009,Sep,01;40(9):3107-12; (PMID: 19520991)
[...] described the time course of early cellular changes in the CNS. For neuroprotection by MC stabilization, pups were treated with Cromolyn (CR) during the initial 24 hours post-HI; brains were examined through 4 weeks.[...]

Development of a rapid and automatic optosensor for the determination of cromolyn in biological samples.

Talanta 2009,Aug,15;79(3):627-32; (PMID: 19576422)
Disodium cromoglycate (SCG) is an anti-allergic drug, which is applied locally or inhaled. After administration, a very small portion of the drug is absorbed, being the most eliminated part unchanged in the urine and bile;[...]

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice.

Nat Med 2009,Aug,01;15(8):940-5; (PMID: 19633655) [FULL TEXT AVAILABLE]
Although mast cell functions have classically been related to allergic responses, recent studies indicate that these cells contribute to other common diseases such as multiple sclerosis, rheumatoid arthritis, atherosclerosis, aortic aneurysm and cancer. This study presents evidence that mast cells also contribute to diet-induced obesity and [...]

The effects of disodium cromoglycate on enhanced adherence of Haemophilus influenzae to A549 cells infected with respiratory syncytial virus.

Pediatr Res 2009,Aug,01;66(2):168-73; (PMID: 19390482)
[...] adherence to airway epithelial cells. In this study, we investigated the effects of disodium cromoglycate (DSCG) and corticosteroids, which are frequently used for the treatment of wheezing often related to [...]
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