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Behav Brain Res 2010,Dec,25;214(2):254-9; (PMID: 20553765)
Caffeine is a psychostimulant with positive effects on cognition. Recent studies have suggested the participation of the cholinergic system in the effects of [...]
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Behav Brain Res 2010,Dec,20;215(1):39-44; (PMID: 20600342)
[...]) since it displays behavioural and neurochemical features of ADHD. Increasing evidence suggests that caffeine might represent an important therapeutic tool for the treatment of ADHD and we recently demonstrated that the acute administration of [...]
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J Pharm Biomed Anal 2010,Nov,02;53(3):396-402; (PMID: 20547027)
[...] and caffeine anhydrate were used as APIs, and tablets were made by the direct compression method. Their NIR spectra were measured in the transmittance mode. The reference assay was performed by [...]
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Cancer Lett 2010,Oct,01;296(1):55-64; (PMID: 20413215)
[...] in variety of cancer cell lines. However, GA-induced p53 activation could be partially reversed by caffeine, a PI3k inhibitor. Therefore, questions of whether GA induces post-translational modifications of p53 and subsequent activation of [...]
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Paediatr Drugs 2010,Oct,01;12(5):301-11; (PMID: 20799759)
[...] downregulates pro-inflammatory cytokines such as tumor necrosis factor-alpha, interleukin-6, and interferon-gamma. Methylxanthines, including caffeine, theophylline, and theobromine are relatively non-toxic drugs; of these, theobromine is the least toxic.[...]
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Antioxid Redox Signal 2010,Sep,15;13(6):745-56; (PMID: 20136509)
[...] Ca(2+) accumulation, and specific respiratory-chain inhibitors. The results obtained were validated by experiments performed with intact cells, by using caffeine (Cf ) to promote mitochondrial Ca(2+) accumulation. Under these conditions, low concentrations of peroxynitrite[...]
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Eur J Pharmacol 2010,Sep,15;643(1):63-9; (PMID: 20599931)
[...] (NMDG(+)) also blocked the inward currents. The inward currents were abolished by caffeine, carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone (FCCP), thapsigargin and ryanodine, but were partly inhibited by [...]
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J Colloid Interface Sci 2010,Sep,15;349(2):498-504; (PMID: 20579657)
[...]We find that the presence of a colloidal shell does indeed reduce the rate of transport of three model molecules: Aspirin, caffeine, and FITC-dextran with MW of approximately 3000-5000. Contrary to expectation, however, we find that for all three molecules the reduction in transport rate is largely independent of the dimensions of the particles composing the shell, despite differences that range over three orders of magnitude.[...]
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Int J Pharm 2010,Sep,15;397(1-2):36-43; (PMID: 20600716)
[...]This study employed molecular dynamics simulation to investigate solute interactions of a model system consisting of a hydrotropic agent, caffeine (CAF), a poorly water-soluble solute, riboflavin (RBF), and water. The study demonstrates that [...]
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Theriogenology 2010,Sep,15;74(5):863-70; (PMID: 20537694)
[...]Boar spermatozoa were diluted at 1 x 10(8) cells/mL with a diluent containing 20% seminal fluid and flowed with modified TCM-199 (mM199, with 5 mM caffeine) to introduce motile sperm into the exit chamber for IVF. In Experiment 1, after flowing for 5 min, sperm concentration varied significantly among specific sites within the MFSS collecting chamber (range, 0.8 +/- 0.5 x 10(4) to 575.0 +/- 56.3 x 10(4) cells/mL; mean +/- SEM).[...]
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