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Results for "Anzemet": Medline ( 197 ) | Full Text ( 10 ) | Grants ( 0 )

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Effect of casopitant, a novel NK-1 antagonist, on the pharmacokinetics of dolasetron and granisetron.

Support Care Cancer 2009,Sep,01;17(9):1187-93; (PMID: 19205754) [FULL TEXT AVAILABLE]
[...]vomiting, on the pharmacokinetics of the commonly prescribed 5-hydroxytryptamine receptor 3 receptor antagonists, dolasetron or granisetron. MATERIALS AND METHODS: In a phase I, open-label, two-part, two-period, single-sequence study, two cohorts of healthy subjects received either oral [...]

Palonosetron plus dexamethasone versus granisetron plus dexamethasone for prevention of nausea and vomiting during chemotherapy: a double-blind, double-dummy, randomised, comparative phase III trial.

Lancet Oncol 2009,Feb,01;10(2):115-24; (PMID: 19135415)
[...] is a second-generation 5-hydroxytryptamine 3 (5-HT(3))-receptor antagonist that has shown better efficacy than ondansetron and dolasetron in preventing chemotherapy-induced nausea and vomiting (CINV) in patients receiving moderately emetogenic chemotherapy, and similar efficacy to [...]

Current management of vomiting after tonsillectomy in children.

Curr Drug Saf 2009,Jan,01;4(1):62-73; (PMID: 19149526)
[...], and midazolam. Serotonin receptor antagonists, which include ondansetron, granisetron, tropisetron, dolasetron, and ramosetron, are more effective than traditional antiemetics. However, these drugs are not entirely effective, perhaps because most of them act through the blockade on one type of receptor.[...]

Palonosetron: in the prevention of nausea and vomiting.

Drugs 2009,Jan,01;69(16):2257-78; (PMID: 19852528)
[...]palonosetron was noninferior to intravenous ondansetron (with statistically greater efficacy than ondansetron) or dolasetron in preventing CINV following MEC, or to intravenous ondansetron or granisetron in preventing CINV following HEC, in the acute phase.[...]

Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II.

Clin Pharmacokinet 2009,Jan,01;48(12):761-804; (PMID: 19902987)
[...], and proper dose adjustment may be needed when the CYP2D6 genotype is determined in a patient. Dolasetron, ondansetron and tropisetron, all in part metabolized by CYP2D6, are less effective in UMs than in other [...]

Dolasetron and QT interval.

Emerg Med J 2008,Oct,01;25(10):706; author reply 706; (PMID: 18843085)

The acute effect of tropisetron on ECG parameters in cancer patients.

Support Care Cancer 2008,Sep,01;16(9):1011-5; (PMID: 18239945)
[...]OBJECTIVES: The 5-hydroxytryptamine 3 receptor antagonists, including tropisetron, ondansetron, granisetron, and dolasetron are agents used effectively for supportive care. They are used for the prevention and treatment of [...]

Is dolasetron the only possible culprit?

J Clin Anesth 2008,Sep,01;20(6):478; (PMID: 18929294)

Reducing the incidence of 131I-induced sialadenitis: the role of pilocarpine.

J Nucl Med 2008,Apr,01;49(4):546-9; (PMID: 18344428)
[...] therapy, would reduce salivary symptoms. All patients received 8 mg of dexamethasone and 100 mg of dolasetron mesylate orally 2 h before therapy and every 12 h for another 5 doses after 131I[...]

Postoperative nausea and vomiting after surgery for prognathism: not only a question of patients' comfort. A placebo-controlled comparison of dolasetron and droperidol.

J Craniomaxillofac Surg 2008,Apr,01;36(3):173-9; (PMID: 18353666)
INTRODUCTION: The aim of this study was to evaluate the efficacy of dolasetron and droperidol (DHB) for preventing postoperative nausea and vomiting (PONV) in patients undergoing surgery for [...]
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