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Results for "Actigall": Pubmed ( 2,762 ) | Free Full Text ( 76 ) | U.S. Grants ( 67 )

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Application of near infrared spectroscopy for rapid analysis of intermediates of Tanreqing injection.

J Pharm Biomed Anal 2010,Nov,02;53(3):350-8; (PMID: 20457503)
[...]The concentrations of chlorogenic acid, caffeic acid, luteoloside, baicalin, ursodesoxycholic acid (UDCA), and chenodeoxycholic acid (CDCA) were determined with the HPLC-DAD/ELSD as reference method.[...]

Enhanced hepatic Nrf2 activation after ursodeoxycholic acid treatment in patients with primary biliary cirrhosis.

Antioxid Redox Signal 2010,Aug,01;13(3):259-68; (PMID: 20055754)
The cytoprotective mechanisms of ursodeoxycholic acid (UDCA) in primary biliary cirrhosis (PBC) have not been fully clarified.[...]

In PSC with dominant bile duct stenosis, IBD is associated with an increase of carcinomas and reduced survival.

J Hepatol 2010,Aug,01;53(2):313-7; (PMID: 20472317)
[...]BACKGROUND & AIMS: In patients with primary sclerosing cholangitis (PSC) treated with ursodeoxycholic acid (UDCA), dominant stenoses are associated with reduced survival free of liver transplantation and the role of [...]

Low incidence of hepatic veno-occlusive disease in pediatric patients undergoing hematopoietic stem cell transplantation attributed to a combination of intravenous heparin, oral glutamine, and ursodiol at a single transplant institution.

Pediatr Transplant 2010,Aug,01;14(5):618-21; (PMID: 20051023)
[...] who underwent HSCT and received a combined prophylactic regimen of intravenous heparin, oral glutamine, and ursodiol was undertaken. Analysis of the outcome of VOD revealed only one clinical case with acute myeloid leukemia[...]

Treatment options for primary sclerosing cholangitis.

Expert Rev Gastroenterol Hepatol 2010,Aug,01;4(4):473-88; (PMID: 20678020)
[...]Despite extensive research, there is currently no effective medical treatment. Multiple drugs are shown to be ineffective in halting disease progression, including ursodeoxycholic acid, the most widely evaluated drug. High-dose ursodeoxycholic acid (28-30 mg/kg/day) was recently shown to increase the adverse events rate.[...]

The cholangiographic features of severe forms of ABCB4/MDR3 deficiency-associated cholangiopathy in adults.

Gastroenterol Clin Biol 2010,Aug,01;34(6-7):380-7; (PMID: 20537830)
[...] dilations that could suggest a specific genetic background in this setting. This variant shows similar sensitivity to ursodeoxycholic acid and may be partly reversible under long-term therapy. In summary, we describe here a peculiar cholangiographic phenotype of the LPAC syndrome characterized by single-shaped large [...]

Effect of ursodeoxycholic acid on inflammatory infiltrate in gallbladder muscle of cholesterol gallstone patients.

Neurogastroenterol Motil 2010,Aug,01;22(8):866-73, e232; (PMID: 20426797)
[...]) contractility and chronic inflammatory changes in the mucosa have been reported in patients with cholesterol gallstones (GS). Ursodeoxycholic acid (UDCA) restores GB contractility and antagonises liver macrophage activation. In the colon[...]

Biliary secretion of S-nitrosoglutathione is involved in the hypercholeresis induced by ursodeoxycholic acid in the normal rat.

Hepatology 2010,Aug,01;52(2):667-77; (PMID: 20683964)
Ursodeoxycholic acid (UDCA) induces bicarbonate-rich hypercholeresis by incompletely defined mechanisms that involve the stimulation of [...]

High-dose ursodeoxycholic acid therapy for nonalcoholic steatohepatitis: a double-blind, randomized, placebo-controlled trial.

Hepatology 2010,Aug,01;52(2):472-9; (PMID: 20683947)
In uncontrolled clinical studies, ursodeoxycholic acid (UDCA) had a beneficial effect on nonalcoholic steatohepatitis (NASH). However, a large controlled trial using [...]

Excessive collagen accumulation in dystrophic (mdx) respiratory musculature is independent of enhanced activation of the NF-kappaB pathway.

J Neurol Sci 2010,Jul,15;294(1-2):43-50; (PMID: 20471037) [FULL TEXT AVAILABLE]
[...]. Various inhibitors of this pathway, such as pyrrolidine dithiocarbamate (PDTC) and ursodeoxycholic acid (UDCA), have been shown to have beneficial effects on dystrophic (mdx) muscle.[...]
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