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Methods Mol Biol 2010,Jan,01;592:149-61; (PMID: 19802595)
In this chapter, we present a brief overview of current knowledge about the promoters of plant microRNAs (miRNAs), and provide a step-by-step guide for predicting plant miRNA promoter elements using known transcription factor binding motifs. The approach to promoter element prediction is based on a carefully constructed collection of Positional Weight Matrices (PWMs) for known transcription[...]
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Clin Exp Med 2009,Dec,01;9(4):339-42; (PMID: 19458910)
[...]cellular immunities. Defects in recombinating activating gene 1 (RAG1), RAG2, Artemis, or LIG4 can disrupt V(D)J recombination. Defective V(D)J recombination of the T and B cell receptors is responsible for T(-)B(-)NK(+)[...]
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Curr Opin Allergy Clin Immunol 2009,Dec,01;9(6):503-9; (PMID: 19823081)
[...] presented as a classical SCID patient, not different from a recombination activating gene or Artemis deficiency. The mutation concerned a hypomorphic missense mutation (L3062R) that did not result in absence of protein expression nor in deficient in vivo or in vitro (auto)phosphorylation.[...]
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J Med Virol 2009,Dec,01;81(12):2059-65; (PMID: 19856480)
The aim of the study was to evaluate the prevalence and risk factors of HPV in a gynecologic population attending outpatient clinics using two new molecular tests. The Amplicor HPV test and the Linear Array (LA) HPV Genotyping test were used for the detection of HPV DNA in 320 women. Multiple logistic regression was used to identify independent prognostic factors of HPV positivity.[...]
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Bioinformatics 2009,Dec,01;25(23):3049-55; (PMID: 19789267)
MicroRNAs (miRNAs) are a class of short endogenously expressed RNA molecules that regulate gene expression by binding directly to the messenger RNA of protein coding genes. They have been found to confer a novel layer of genetic regulation[...]
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Am J Forensic Med Pathol 2009,Dec,01;30(4):384-5; (PMID: 19901811)
The number of drug-facilitated sexual assault incidents has lately been increased all over the world leading law enforcement agencies and hospital doctors to constant alert. The drugs involved may be [...]
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Fertil Steril 2009,Dec,01;92(6):2078-81; (PMID: 19700156)
Diagnosis of polycystic ovary syndrome (PCOS), at present very common in women of reproductive age, is implicated with potential long-term metabolic consequences that are difficult to be investigated due to the heterogeneity in the manifestation of the syndrome.[...]
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EMBO J 2009,Nov,04;28(21):3413-27; (PMID: 19779458)
[...]) represent distinct pathways for repairing DNA double-strand breaks (DSBs). Previous work implicated Artemis and ATM in an NHEJ-dependent process, which repairs a defined subset of radiation-induced DSBs[...]
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Klin Monbl Augenheilkd 2009,Nov,01;226(11):914-20; (PMID: 19798624)
This review highlights recent advances in clinical research on the therapy for retinopathy of prematurity (ROP). This disease is still important, because improvements in neonatal intensive care during the last years have increased the survival of the most [...]
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Nucleic Acids Res 2009,Nov,01;37(20):6737-45; (PMID: 19762482)
[...] was totally dependent on XrccIV, and altered in the absence of Ku80. In contrast, Artemis appears to be specifically involved in cDSB repair. These results may indicate that mammalian cells have a damage control strategy, whereby severe [...]
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