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Results for refsum disease: Pubmed ( 931 ) | Free Full Text ( 141 ) | U.S. Grants ( 13 )

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Antipsychotic treatments for the elderly: efficacy and safety of aripiprazole.

Neuropsychiatric Disease and Treatment 2010,Jan,01;6:47-58 (PMCID: 2846120)
[...] in the elderly including schizophrenia, bipolar disorder, dementia, Parkinson’s disease and depression. We will review the pharmacokinetics and pharmacodynamics of aripiprazole as well as dosing, diagnostic indications, efficacy studies, and tolerability including its [...]

Levels of circulating homocysteine, vitamin B6, vitamin B12, and folate in different types of open-angle glaucoma.

Clin Interv Aging 2010,Jan,01;5:133-139 (PMCID: 2861848)
[...]The systemic examination was performed and a detailed medical story was obtained to identify the patients with risk factors for vascular disease such as hypertension, diabetes mellitus, hyperlipidemia, cardiovascular, and cerebrovascular diseases. Blood[...]

Cobalamin deficiency, hyperhomocysteinemia, and dementia.

Neuropsychiatric Disease and Treatment 2010,May,06;6:159-195 (PMCID: 2874340)
[...] generally respond favorably to supplemental B12 treatment, especially if pernicious anemia is diagnosed early in the course of the disease. Some patients without pernicious anemia, but with B12 deficiency and either mild cognitive impairment[...]

Synthesis of 5-Hydroxyectoine from Ectoine: Crystal Structure of the Non-Heme Iron(II) and 2-Oxoglutarate-Dependent Dioxygenase EctD.

plosone 2010,Jan,01;5(5) (PMCID: 2871039, DOI: 10.1371/journal.pone.0010647)
* E-mail: xxxx@xxxx.xx (KR); xxxx@xxxx.xx (EB). [...]

Epistatic and Functional Interactions of Catechol-O-Methyltransferase (COMT) and AKT1 on Neuregulin1-ErbB Signaling in Cell Models.

plosone 2010,Jan,01;5(5) (PMCID: 2875391, DOI: 10.1371/journal.pone.0010789)
[...]schizophrenia, and their associations with these disease conditions have been extensively studied [4], [6].

Effect of lipopenic and hypotensive treatment on homocysteine levels in type 2 diabetics.

Vascular Health and Risk Management 2010,Jan,01;6:327-332 (PMCID: 2879294)
[...] constitutes a major public health problem that leads to the development of various chronic complications. Macrovascular disease represents the main cause of mortality in patients with diabetes. In fact, the damage of the endothelial wall plays an important role in the development of [...]

Impulsivity, gender, and the platelet serotonin transporter in healthy subjects.

Neuropsychiatric Disease and Treatment 2010,Jan,01;6:9-15 (PMCID: 2819761)
Correspondence: Donatella Marazziti, Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, University of Pisa, via Roma, 67, I-56100 Pisa, Italy, Tel + 39 050 835412, Fax + 39 050 21581 Email xxxx@xxxx.xx. [...]

Antidepressants are a rational complementary therapy for the treatment of Alzheimer's disease.

Mol Neurodegener 2010,Jan,01;5:10-10 (PMCID: 2845130, DOI: 10.1186/1750-1326-5-10)
There is a high prevalence rate (30-50%) of Alzheimer's disease (AD) and depression comorbidity. Depression can be a risk factor for the development of [...]

A1298C polymorphism in the MTHFR gene predisposes to cardiovascular risk in rheumatoid arthritis.

Arthritis Res Ther 2010,Jan,01;12(2):R71-R71 (PMCID: 2888227, DOI: 10.1186/ar2989)
[...]rheumatoid arthritis (RA) have increased risk of cardiovascular (CV) disease due to accelerated atherosclerosis [1]. Besides classic CV risk factors, a number of nontraditional CV risk factors have also been implicated in the elevated CV mortality observed in these [...]

Easy retrieval of single amino-acid polymorphisms and phenotype information using SwissVar.

bioinfo 2010,Mar,15;26(6):851-852 (PMCID: 2832822, DOI: 10.1093/bioinformatics/btq028)
[...]The current challenge is how to optimally exploit this data to better understand disease association and accelerate the pace towards personalized treatments. Indeed, there are still numerous unanswered questions on the exact relationship between genetic variations, phenotypes and diseases.[...]
[...]For example, the users can query for all proteins related to metabolism diseases, and gather in one click proteins and variants related to refsum disease, gout etc. The representation of the MeSH hierarchy further enables the visualization and navigation inside the categories of diseases in which the queried proteins are implicated.[...]
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