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J Virol 2010,Aug,01;84(15):7418-26; (PMID: 20375160) [FULL TEXT AVAILABLE]
[...] in infancy, childhood pneumonia, and acute exacerbations of chronic respiratory diseases such as asthma, chronic obstructive lung disease, and cystic fibrosis. Until a few years ago, only two groups of HRVs (A and B) had been recognized.[...]Risk factors and pathogenic mechanisms for more-severe HRV infections are being defined, and yet fundamental questions persist about mechanisms relating this common pathogen to allergic diseases and asthma. The close relationship between HRV infections and asthma suggests that antiviral treatments could have a major impact on the morbidity associated with this [...]
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Exp Hematol 2010,Jul,01;38(7):548-56; (PMID: 20303382)
[...]Recent data obtained from the clinical setting suggests that the enumeration of circulating fibrocytes may be a biomarker for disease progression in chronic lung diseases including asthma and pulmonary fibrosis. A greater understanding of the immunologic mediators that influence fibrocyte biology suggests new opportunities for therapeutic manipulation of these cells in [...]
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Am Fam Physician 2010,Jun,15;81(12):1440-6; (PMID: 20540482)
[...] is a common chronic respiratory illness that affects quality of life, productivity, and other comorbid conditions, including asthma. Treatment should be based on the patient's age and severity of symptoms. Patients[...]
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Am J Respir Crit Care Med 2010,Jun,15;181(12):1294-309; (PMID: 20167850)
[...], which include pneumonia, chronic obstructive pulmonary disease, acute lung injury, pneumoconioses, and asthma. PRRs are capable of sensing different microbes as well as endogenous molecules that are released after [...]
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Orv Hetil 2010,Jun,06;151(23):941-5; (PMID: 20494889)
[...], decreasing the time of exposure, substitution of the irritant agent, investigation of possible asthma in all workers with OR. Medical treatments are: oral antihistamines, local (nasal) corticosteroids, combined (antihistamine+membrane-stabilizer) eyedrops.[...]
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Am J Physiol Lung Cell Mol Physiol 2010,Jun,01;298(6):L715-31; (PMID: 20363851) [FULL TEXT AVAILABLE]
[...]Both localized and distal progenitor stem cells are recruited into the injured area, and proliferation and phenotypic differentiation of these cells leads to recovery of epithelial function. Persistent injury may contribute to the pathology of diseases such as asthma, chronic obstructive pulmonary disease, and pulmonary fibrosis. For example, dysregulated repair processes involving [...]
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Dtsch Med Wochenschr 2010,Jun,01;135(25-26):1278-80; (PMID: 20556682)
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J Allergy Clin Immunol 2010,Jun,01;125(6):1190-9; quiz 1200-1; (PMID: 20471068) [FULL TEXT AVAILABLE]
[...]Human rhinovirus (HRV) infection is the cause of about one half of asthma and chronic obstructive pulmonary disease exacerbations. With more than 100 serotypes in the HRV reference set, an effort was undertaken to sequence their complete genomes so as to understand the diversity, structural variation, and evolution of the virus.[...]
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Ann Allergy Asthma Immunol 2010,Jun,01;104(6):455-60; quiz 461-3, 484; (PMID: 20568376)
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Chest 2010,Jun,01;137(6):1417-26; (PMID: 20525652)
There has been an increased understanding, over the past 2 decades, that asthma is a chronic, immunologically mediated condition with a disturbance of the normal airway repair mechanism, which results in inflammatory changes and airway remodeling.[...]
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