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Ann Allergy Asthma Immunol 2010,Jun,01;104(6):518-22; (PMID: 20568385)
BACKGROUND: Acquired cold urticaria (ACU) is a form of physical urticaria that has been treated with first-generation antihistamines; there is a paucity of data regarding second- and third-generation antihistamines for the treatment of [...]
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J Asthma 2010,May,01;47(4):439-46; (PMID: 20528600)
BACKGROUND: Current asthma guidelines recommend the use of long-acting beta-agonists (LABAs) in combination with inhaled corticosteroids (ICSs) for long-term control and prevention of symptoms in persistent [...]
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Arch Dis Child 2010,May,01;95(5):365-70; (PMID: 19946008)
[...] corticosteroids (ICS) versus montelukast (MONT) in schoolchildren and adolescents with mild-moderate persistent asthma. METHODS: Randomised, prospective, controlled trials published January 1996 to November 2009 with a minimum of 4 weeks of ICS versus [...]
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Am J Med 2010,Apr,01;123(4):322-8.e2; (PMID: 20176343)
BACKGROUND: It is unclear whether long-acting beta-agonists with concomitant inhaled corticosteroids increase asthma-related intubations and deaths. We pooled data on long-acting beta-agonists with variable and concomitant inhaled[...]
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Ann Allergy Asthma Immunol 2010,Apr,01;104(4):286-92; (PMID: 20408337)
OBJECTIVE: To compare autoimmune lymphoproliferative syndrome (ALPS) and Stevens-Johnson syndrome (SJS) with respect to the defects in Fas- and Fas ligand (FasL[...]
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Am J Epidemiol 2010,Apr,01;171(7):749-64; (PMID: 20228139) [FULL TEXT AVAILABLE]
[...]To summarize the available epidemiologic evidence, the authors performed a meta-analysis of associations between atopy/allergies, asthma, eczema, hay fever, and hives and childhood/adolescent leukemia, acute lymphoblastic leukemia ([...]
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Curr Med Res Opin 2010,Apr,01;26(4):925-32; (PMID: 20163297)
[...] data (IPD) meta-analysis was performed of three open, prospective observational studies on high-dose SLIT using IR-standardised allergen extracts in patients with allergic rhinitis with and without asthma. RESULTS: In total, 1052 patients aged 24.9 years (mean) were treated with SLIT and included in this IPD meta-analysis.[...]
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Environ Health Perspect 2010,Apr,01;118(4):449-57; (PMID: 20064785) [FULL TEXT AVAILABLE]
[...]OBJECTIVE: Our goal was to quantify the short-term effects of particulate matter with aerodynamic diameter < or = 10 microm (PM10) and nitrogen dioxide (NO2) on respiratory health of asthmatic children from published panel studies, and to investigate the influence of study and population characteristics as effect modifiers.[...]14 were part of the European Pollution Effects on Asthmatic Children in Europe (PEACE) study. Adverse associations of PM10 with asthma symptoms were statistically significant [odds ratio (OR) = 1.028; 95% confidence interval (CI), 1.006-1.051]. There were also associations, although not statistically significant, of PM10 with [...]
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Int J Epidemiol 2010,Apr,01;39(2):539-62; (PMID: 20032267) [FULL TEXT AVAILABLE]
BACKGROUND: Oxidative stress is thought to be involved in the pathogenesis of asthma. Glutathione-S-transferase (GST) enzymes, which play an important role in antioxidant defences, may therefore influence [...]
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Int J Epidemiol 2010,Apr,01;39(2):469-86; (PMID: 19822573)
[...]BACKGROUND: Results have been conflicting as to whether Bacillus Calmette-Guérin (BCG) vaccine, a non-specific stimulator of the immune function, protects, predisposes or is unrelated to the development of childhood asthma. In this systematic review and meta-analysis, we qualitatively and quantitatively appraised the epidemiological evidence.[...]CONCLUSION: These results strengthen the epidemiological evidence in support of the hypothesis that exposure to the BCG vaccine in early life prevents asthma, possibly through a modulation of the immune maturation process.
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