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Results for Collins,F: Pubmed ( 1,929 ) | Free Full Text ( 52 ) | U.S. Grants ( 28 )

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A randomized, controlled trial of early versus late initiation of dialysis.

N Engl J Med 2010,Aug,12;363(7):609-19; (PMID: 20581422)
BACKGROUND: In clinical practice, there is considerable variation in the timing of the initiation of maintenance dialysis for patients with stage V chronic kidney disease, with a worldwide trend toward early initiation. In this study, conducted at 32 centers in Australia and New Zealand, we examined whether the timing of the initiation of maintenance dialysis influenced survival among [...]

Biological, clinical and population relevance of 95 loci for blood lipids.

Nature 2010,Aug,05;466(7307):707-13; (PMID: 20686565)
Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides are among the most important risk factors for coronary artery disease (CAD) and are targets for therapeutic intervention.[...]

Evaluating clinical applicability: the STICH trial's findings.

J Am Coll Cardiol 2010,Aug,03;56(6):508-9; (PMID: 20670762)

The path to personalized medicine.

N Engl J Med 2010,Jul,22;363(4):301-4; (PMID: 20551152)

Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle.

Proc Natl Acad Sci U S A 2010,Jul,06;107(27):12168-73; (PMID: 20566863) [FULL TEXT AVAILABLE]
As an obligatory parasite of humans, the body louse (Pediculus humanus humanus) is an important vector for human diseases, including epidemic typhus, relapsing fever, and trench [...]

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.

Nat Genet 2010,Jul,01;42(7):579-89; (PMID: 20581827)
By combining genome-wide association data from 8,130 individuals with type 2 diabetes (T2D) and 38,987 controls of European descent and following up previously unidentified meta-analysis signals in a further 34,412 cases and 59,925 controls, we identified 12 new [...]

Patient-centered outcomes research institute: the intersection of science and health care.

Sci Transl Med 2010,Jun,23;2(37):37cm18; (PMID: 20574065)
The Patient Protection and Affordable Care Act created the Patient-Centered Outcomes Research Institute (PCORI), a nonprofit corporation that is neither an agency nor an establishment of the U.S. government.[...]

Managing financial conflict of interest in biomedical research.

JAMA 2010,Jun,16;303(23):2400-2; (PMID: 20498237)

Using science to improve the nation's health system: NIH's commitment to comparative effectiveness research.

JAMA 2010,Jun,02;303(21):2182-3; (PMID: 20516419)

Newsmaker interview. Francis Collins: on recruiting Varmus, discovering drugs, the funding cliff. Interview by Jocelyn Kaiser.

Science 2010,May,28;328(5982):1090-1; (PMID: 20508101)
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