|
|
|
|
|
|
|
Am J Med Genet B Neuropsychiatr Genet 2010,Sep,01;153B(6):1179-88; (PMID: 20468071)
[...]Twin studies provide strong evidence that there is a shared genetic liability that predisposes to a number of different psychiatric outcomes related to behavioral disinhibition. Further, alcohol dependence comorbid with other disinhibitory disorders is particularly heritable. Chromosome 2p14-2q14.3 has been linked to multiple psychiatric conditions related to [...] 2p14-2q14.3 has been linked to multiple psychiatric conditions related to behavioral undercontrol. In the Collaborative Study on the Genetics of Alcoholism (COGA), we previously reported linkage to this region with alcohol dependence (AD), [...]
|
|
|
Am J Med Genet B Neuropsychiatr Genet 2010,Sep,01;153B(6):1250-1; (PMID: 20552679)
|
|
|
Am J Med Genet B Neuropsychiatr Genet 2010,Sep,01;153B(6):1119-26; (PMID: 20552678)
While strong familial evidence supports a substantial genetic contribution to the etiology of autism spectrum disorders (ASD), specific genetic abnormalities have been identified in only a small minority of all cases.[...]
|
|
|
Am J Med Genet B Neuropsychiatr Genet 2010,Sep,01;153B(6):1160-6; (PMID: 20468063)
[...]Cytochrome P450 2C19 (CYP2C19) is a polymorphic enzyme active in the metabolism of for example diazepam and the antidepressants sertraline, citalopram, and escitalopram, whereby allelic variants cause increased ([...]
|
|
|
Am J Med Genet B Neuropsychiatr Genet 2010,Sep,01;153B(6):1209-20; (PMID: 20468076)
[...]The biologic basis of autism is complex and is thought to involve multiple and variable gene-environment interactions. While the logical focus has been on the affected [...], the impact of maternal genetics on intrauterine microenvironment during pivotal developmental windows could be substantial. Folate-dependent one carbon metabolism is a highly polymorphic pathway that regulates the distribution of one-[...]
|
|
|
Am J Med Genet B Neuropsychiatr Genet 2010,Sep,01;153B(6):1127-33; (PMID: 20607790)
[...]Although our sample size is smaller (415 trios vs. 909), the power was sufficient to confirm the role of candidate markers in ADHD if a true association exists. Two out of 36 top SNPs were significant at alpha = 0.05 in our sample, although none was still significant after correction for multiple tests.[...]
|
|
|
Am J Med Genet B Neuropsychiatr Genet 2010,Sep,01;153B(6):1221-7; (PMID: 20468077)
[...]) gene encodes phosphohippolin that regulates cellular ion transport by altering the kinetic properties of Na,K-ATPase. Phosphohippolin is highly expressed in brain regions that are relevant to schizophrenia.[...]
|
|
|
Biol Blood Marrow Transplant 2010,Sep,01;16(9):1187-211; (PMID: 20558311)
[...]Relapse has become the major cause of treatment failure after allogeneic stem cell transplantation. Outcome of patients with clinical relapse after transplantation generally remains poor, but intervention prior to florid [...]relapse or minimal residual disease, sensitive methods such as molecular genetics, tumor-specific molecular primers, fluorescein in situ hybridization, and multiparameter flow cytometry (MFC) are commonly used after allogeneic stem cell transplantation[...]
|
|
|
Am J Physiol Endocrinol Metab 2010,Sep,01;299(3):E446-55; (PMID: 20570823)
[...]Sociability and gender preference were assessed by three-chambered choice tasks before and after castration and after testosterone replacement. Metabolomic activities of brain and blood were quantified through fractional synthesis rates of palmitate and ribose (GC-MS). XXY [...] and their odors are due to social rather than sexual cues and, these differences are mostly related to androgen deficiency rather than genetics. Specific metabolic changes in brain lipids, which are also regulated by androgens, are observed in [...]
|
|
|
Am J Surg Pathol 2010,Sep,01;34(9):1295-303; (PMID: 20679884)
[...]however, their profile in reference to other IHC markers that are differentially expressed in other subtypes of RCC has not been systematically assessed. Few therapeutic targets have been identified in these aggressive [...]We created 2 tissue microarrays (TMA) containing five 1.4-mm cores from each of 21 Xp11 translocation RCC (all confirmed by TFE3 IHC, 6 further confirmed by genetics), 7 clear cell RCC (CCRCC), and 6 papillary RCC (PRCC). These TMA were labeled for a panel of IHC markers.[...]
|
 1 2 3 4 5 6 7 8 
|
|
|
|
|
