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J Immunol 2010,Aug,01;185(3):1846-54; (PMID: 20574000)
[...]Antagonists of the type 1 cysteinyl leukotriene receptor (CysLT(1)R) are efficacious for bronchoconstriction in humans with bronchial asthma; however, the clinical response to these drugs is heterogeneous. In particular, how CysLT(1)R expression and function are constitutively regulated in vivo is not known.[...]
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Chest 2010,Aug,01;138(2 Suppl):4S-10S; (PMID: 20668012)
Airway hyperresponsiveness (AHR) is a clinical feature of asthma and is often in proportion to the underlying severity of the disease. To understand AHR and the mechanisms that contribute to these processes, it is helpful to divide the airway components that affect this feature of [...]
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Immunol Allergy Clin North Am 2010,Aug,01;30(3):397-409; (PMID: 20670821)
This review examines the scientific evidence behind the hypothesis that vitamin D plays a role in the pathogenesis of allergic diseases, along with a focus on emerging data regarding vitamin D and atopic dermatitis.[...]
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Am J Respir Cell Mol Biol 2010,Aug,01;43(2):179-91; (PMID: 19767449)
The etiology of airway hyperresponsiveness associated with asthma requires an understanding of the regulatory mechanisms mediating human airway smooth muscle cell (SMC) contraction.[...]
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Am J Pathol 2010,Aug,01;177(2):525-31; (PMID: 20566752) [FULL TEXT AVAILABLE]
Allergic diseases and asthma are caused by dysregulated Th2-type immune responses, which drive disease development in susceptible individuals.[...]
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Pediatrics 2010,Aug,01;126(2):306-14; (PMID: 20624804)
[...]OBJECTIVES: To identify patterns of shared decision-making (SDM) among a nationally representative sample of US children with attention-deficit/hyperactivity disorder (ADHD) or asthma and determine if demographics, health status, or access to care are associated with SDM. PATIENTS[...]
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J Allergy Clin Immunol 2010,Aug,01;126(2):225-31, 231.e1-4; (PMID: 20569973) [FULL TEXT AVAILABLE]
BACKGROUND: Inhaled corticosteroid (ICS) nonadherence is common among patients with asthma; however, interventions to improve adherence have often been complex and not easily applied to large [...]
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J Allergy Clin Immunol 2010,Aug,01;126(2):241-9, 249.e1-3; (PMID: 20624651)
BACKGROUND: The genetic mechanisms underlying asthma remain unclear. Increased permeability of the microvasculature is a feature of asthma, and the sphingosine-1-phosphate receptor (S1PR1) is an essential participant regulating [...]
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J Occup Environ Med 2010,Aug,01;52(8):827-8; (PMID: 20657304)
OBJECTIVES: This study examined associations of asthma with school commuting time. METHODS: Time on likely school commute route was used as a proxy for on-road air pollution exposure among 4741 elementary school [...]
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Ann Allergy Asthma Immunol 2010,Aug,01;105(2):99-106; quiz 107-9, 117; (PMID: 20674819)
[...]STUDY SELECTION: Articles concerning pathophysiologic conditions that link atopic dermatitis, allergic rhinitis, and asthma were examined. RESULTS: The data suggest that a sequence of atopic manifestations occurs, typically atopic dermatitis[...]
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