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Biochem Pharmacol 2010,Feb,01;79(3):444-54; (PMID: 19732755)
Caffeic acid phenethyl ester (CAPE) has recently been shown to potently stimulate glucose uptake in cultured skeletal [...]
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J Cell Physiol 2009,Dec,01;221(3):642-9; (PMID: 19681045)
[...]Receptor activator NF-kappaB ligand (RANKL)-activated signaling is essential for osteoclast differentiation, activation and survival. Caffeic acid phenethyl ester (CAPE), a natural NF-kappaB inhibitor from honeybee propolis has been shown to have anti-tumor and anti-inflammatory properties.[...]
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Biol Pharm Bull 2009,Dec,01;32(12):1947-51; (PMID: 19952409)
[...] extract of bee pollen. Many natural compounds are included in Brazilian green propolis, such as caffeoylquinic acid derivatives [3,4-di-caffeoylquinic acid (3,4-CQA), 3,5-di-caffeoylquinic acid (3,5-CQA), and chlorogenic acid (ChA[...]cinnamic acid derivatives, artepillin C exhibited relatively strong DPPH radical scavenging activity. Caffeic acid phenethyl ester (CAPE), a constituent of Chinese red propolis, exhibited potent DPPH radical scavenging activity, stronger than that of [...]
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World J Gastroenterol 2009,Nov,07;15(41):5181-5; (PMID: 19891017) [FULL TEXT AVAILABLE]
AIM: To evaluate the therapeutic role of caffeic acid phenethyl ester (CAPE) in a rat model of cerulean-induced acute pancreatitis (AP). METHODS: Seventy male Wistar [...]
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Carcinogenesis 2009,Nov,01;30(11):1941-8; (PMID: 19759193) [FULL TEXT AVAILABLE]
[...]) could abrogate the inflammatory response to metastatic breast cancer cells by modulating NF-kappaB. Caffeic acid phenethyl ester and parthenolide inhibited NF-kappaB activation, as seen by gel shift assays and immunoblotting for p65 in nuclear fractions, as well as decreased production of [...]
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Int J Cancer 2009,Oct,15;125(8):1786-95; (PMID: 19610061)
[...] and carcinogenesis and as such is an important drug target for adjuvant therapy. In this study, we examined the effect of caffeic acid phenethyl ester (CAPE), an NF-kappaB inhibitor, on Helicobacter pylori (H. pylori)-induced NF-kappaB activation in [...]
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Pharmacol Res 2009,Oct,01;60(4):270-6; (PMID: 19717012)
Caffeic acid phenethyl ester (CAPE) was screened for hypoglycemic and liver-protective activity in streptozotocin (STZ[...]
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Planta Med 2009,Sep,01;75(11):1237-40; (PMID: 19330765)
[...]Caffeic acid is a xanthine oxidase (XO) inhibitor that binds to the molybdopterin region of its active site.[...]) inhibitor that binds to the molybdopterin region of its active site. Caffeic acid phenethyl ester (CAPE) has higher hydrophobicity and exhibits stronger inhibition potency toward XO. Chlorogenic acid[...]
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Bioorg Med Chem Lett 2009,Aug,15;19(16):4574-8; (PMID: 19625188)
A series of nitrogen-containing polyhydroxylated aromatics from caffeic acid phenethyl ester were designed and synthesized as HIV-1 integrase inhibitors. Most of these compounds exhibited potent inhibitory[...]
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Food Chem Toxicol 2009,Aug,01;47(8):1980-4; (PMID: 19457442)
Protective effect of caffeic acid phenethyl ester (CAPE) on ovary ischemia/reperfusion (IR) injury was investigated in this study.[...]
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